It is anything but minor
The 86% decrease in liver fat observed with the highest dose is one of the best reported to date
Diabetes Complications 31 , 218222 (2017)
Use of GLP-1 drugs for diabetes or obesity early in the first trimester of pregnancy, before a woman realizes she is pregnant, is not a cause for alarm, a large new data analysis suggests
Cell Metab 17(6):819837 Chang YC, Chan MH, Yang YF, Li CH, Hsiao M (2023) Glucose transporter 4: insulin response mastermind, glycolysis catalyst and treatment direction for cancer progression
After 52 weeks of treatment, the proportion of participants in the oral semaglutide group achieving an A1C of less than 7.0% was 58.3% (treatment-policy estimand) and 62.8% (trial-product estimand), compared with 25.2% (treatment-policy estimand) and 28.3% (trial-product estimand) for the group receiving 100 mg of sitagliptin daily