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Superoxide radical can be generated by specialized enzymes, such as the xanthine or NADPH oxidases, or as a by-product of cellular metabolism, particularly the mitochondrial electron transport chain, and are converted to hydrogen peroxide by the superoxide dismutase (SOD)
While singly-housed animals may experience stress that impacts metabolism, body weight, and adiposity 65,66,67,68,69 , the singly-housed animals in this study were treated identically (to the best of the experimenters ability) to minimize and equalize stress across all animals and reduce confounding variables
As an effective iron chelator, deferoxamine (DFO) can chelate free iron and is used to relieve the damage of iron overload
Its unique extended-release oral suspension allows for convenient nighttime dosing, making it a valuable addition to our holistic treatment plans
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