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If not treated, it can lead to significant brain damage

Additionally, the authors of that study suggest that patients in US clinical practice may have received higher oral semaglutide dosage formulations at first prescription because they had already been prescribed a GLP-1 RA before, which is permitted in the US [18, 24], or because they received samples of higher dosage, thus inflating the proportion of patients receiving higher oral semaglutide formulations [18]

Serious but Rare Risks: When to Seek Medical Help While uncommon, there are serious risks to be aware of

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Working with a counselor can also help develop healthy coping strategies

This chart shows clinical trial protocols from published studies