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10.7759/cureus.44924 18 ChenS.WangX.LiuZ.WangJ.GuoY.WangQ.et al (2023)

Pharmacokinetic and Statistical Analysis Etravirine maximum plasma concentration (Cmax), time to Cmax (Tmax), and Ctrough were derived

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In a separate high content screening study we also demonstrated that many pharmaceuticals falling into this basic lipophilic category cause cell loss, DNA fragmentation, and changes to nuclear size, in addition to the lysosomal mass effects [15]

The compound progressed through Phase 2 trials under multiple sponsors for postoperative ileus and related gastric-motility indications but did not advance to a marketed therapeutic