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This study is the first to systematically demonstrate that the botanical extract LEO ameliorates T2D metabolic disorder via a cascade mechanism: restructuring gut microbiota composition, restoring SCFA-producing bacterial populations, elevating colonic butyrate levels, activating MPC2 expression, and ultimately repairing mitochondrial energy metabolism in enteroendocrine cells to enhance GLP-1 secretion

So Whats the Big Difference

The circulatory system delivers blood to the glomeruli, which are the small filtering units of the kidneys, through small capillaries

Jul 2008;28(7):1225-1236

52 (11), 13741381 (2014) X

It triggers fat breakdown whilst also having a powerful anti-inflammatory effect which reduces swelling and puffiness