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Key Takeaways Ozempic, Wegovy, Zepbound, and Mounjaro do not directly cause hair loss, but rapid weight loss and low nutrient intake during treatment can trigger temporary shedding

The most common complaints involve injection site reactions: redness, swelling, or tenderness that resolves within hours to a day

Hormonal fluctuations during perimenopause can make weight management particularly challenging because they can affect appetite regulation

These drugs mimic that hormone

At the same time, pyruvate accumulation stabilizes and activates hypoxia-induced factor-1 (HIF-1) (even in the bodys physiological oxygenated state) which increases oxidative stress and induces an inflammatory response in the form of, for example, activation of nuclear factor kappa-B (NF-B) and increased expression of tumor necrosis factor- (TNF-) [60,61] (Figure 3)

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