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Identification of an apical Cl /HCO 3 exchanger in the small intestine

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Kelly and Latzko 1979)

Neither dose showed a statistically significant difference from placebo on the primary outcome of colonic transit time or on any of the secondary outcomes.[7] The strain still has a positive evidence base in the broader literature, but the largest single trial in functional constipation was null

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This creates a powerful internal defense system