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Thus, mTORC1 promotes the nuclear translocation of the cAMP response element-binding protein (CREB) which stimulates the transcription of the anti-apoptotic gene MCL-1 in the nucleus and the upregulation of the Bcl-2 family protein myeloid cell leukemia 1 (Mcl-1) [300]

Notably, most animal model acupuncture studies on TBI focused on regulating M1 phenotypic polarization

For storage, bacteriostatic water should be maintained at ambient temperature and protected from light, heat, and moisture

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All animal procedures were done at the AAALAC accredited University of Puerto Rico-Medical Sciences Campus Animal Resources Center and approved by the Institutional Animal Care and Use Committee (Protocol number 2480108)

Blood markers such as hemoglobin and serum B12 typically improve over weeks to months