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As a result, reconstituted peptide solutions remain microbiologically stable across multiple experimental sessions when stored at 4C

In contrast, DIO mice in both groups switched from WD to LD each had significantly increased Proteobacteria relative abundance (represented solely by the genus Parasutterella ) compared to both the WD and the LD controls, suggesting that Proteobacteria relative abundance may be largely influenced by stress or the differences in net energy expenditure (or associated body weight changes) caused by the diet switch

Hematologic and biochemical monitoring throughout the trials revealed no concerning patterns in blood counts, liver function tests, kidney function markers, or other laboratory parameters

Refrigeration or freezing of the lyophilized material is recommended for extended stability, in accordance with laboratory SOPs