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Elevated SAH acts as a biochemical brake on many SAM-dependent methyltransferases

The effective concentrations are remarkably low

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Randomised controlled trials of selenium in thyroid disease Several trials of selenium supplementation have been carried out in AITD/HT and mild Graves orbitopathy

The rate production of the pink pigment was used as a quantitative measure of enzyme activity

Next, the proteins were purified by gel filtration in a Superdex 200 column (Amersham Biosciences Inc., Piscataway, NJ, USA) equilibrated in 20 mM Tris-HCl (pH 8.0) and 150 mM NaCl