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Its endogenous form has a plasma half-life of only 2-3 minutes due to rapid degradation by dipeptidyl peptidase-4 (DPP-4) and renal clearance

Gastrointestinal symptomsincluding nausea, abdominal discomfort, bloating, and altered bowel habitsoccur because Ozempic slows gastric emptying and affects gut motility

Chakraborty A, Hatzis C, DiGiovanna MP

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Adaptations to prey base in the hypercarnivorous leopard cat Prionailurus bengalensis

However, phlebotomy cannot be used in patients with significant anemia, malignancy, or hemodynamic instability, and chelation therapy has an inherent risk of toxicity (4, 40, 41)