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There are a number of possible mechanisms [390], but one perspective is that the pulses produce inhibitory neuronal effects on somata that are proximal to the location of the electrode

Statistical analysis between two groups was assessed using a nonparametric MannWhitney U-test or two-tailed unpaired t -test, depending on the outcome of the normality by the Shapiro-Wilk test

Furthermore, lead exposure was also able to increase ROS levels, decrease antioxidant enzyme activity in vivo, and impair oocyte maturation and fertilization by inducing oxidative stress, leading to the decline of fertility in female mice [77]

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A recent 2022 study demonstrated that not only neurons but also glial cells rely on glutathione for homeostasis (12)

doi: 10.1038/s41590-021-00996-0 98 WangYTianQHaoYYaoWLuJChenCet al