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PMID: 34459213 DOI: 10.1161/CIRCULATIONAHA.121.056824 Packer M et al (2022): Critical Reanalysis of the Mechanisms Underlying the Cardiorenal Benefits of SGLT2 Inhibitors and Reaffirmation of the Nutrient Deprivation Signaling/Autophagy Hypothesis

How they work GLP-1 receptor agonists can help control blood sugar and promote weight loss by mimicking a natural hormone called glucagon-like peptide 1 (GLP-1) in your body

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The PCCA gene is located on chromosome 13q32.3 and is composed of 32 exons that generate eleven alternatively spliced mRNAs, each of which encode a unique protein isoform