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Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) were initially developed for the management of type 2 diabetes, due to their role in enhancing insulin secretion, decreasing glucagon secretion, and delaying gastric emptying
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The combination of naltrexone and semaglutide has emerged as a potential strategy for weight management, with some clinical research suggesting synergistic effects on appetite suppression and metabolism