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Glycosidases are often overexpressed in certain pathological conditions, such as cancer or lysosomal storage diseases, making glycosidase-cleavable linkers an effective tool for achieving site-specific drug activation
doi: 10.4149/bll_2015_092 100 KhalilSRMohammedATAbd El-FattahAHZagloolAW
doi: 10.1016/j.cmet.2015.06.006 59 AndersonME
Reactive oxygen species can be beneficial, as against pathogens, and are also used in cell signalling
Toxicology Research: BPC-157 is investigated in experimental toxicology models involving NSAID-associated gastrointestinal injury, ethanol-associated hepatic damage, and potassium-related systemic toxicity