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Well-designed randomized clinical studies are needed to systematically evaluate the evidence for the use of these hepatoprotective agents as treatment options for APAP-induced liver injury, to determine the timing of initiation of the therapy, and to further define the optimal treatment regimen

[DOI] [PubMed] [Google Scholar] 41.Misener V.L., Schachar R., Ickowicz A., Malone M., Roberts W., Tannock R., Kennedy J.L., Pathare T., Barr C.L

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