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Some patients may remain on the same dose longer because of side effects, medical history, treatment response or provider judgment

10.1164/rccm.201307-1289LE Am J Respir Crit Care Med

Calcium Pyruvate (Medical grade) Calcium pyruvate is a naturally occurring compound that combines calcium with pyruvic acid

Side effects are generally mild and uncommon: bruising at the IV site, a mild cooling sensation during infusion, or a temporary metallic taste with certain vitamins

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Chronic expression of low levels of tumor necrosis factor-alpha in the substantia nigra elicits progressive neurodegeneration, delayed motor symptoms and microglia/macrophage activation