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In the presence of elevated zinc levels, zinc ions bind to the zinc-binding domains of MTF-1

Also, ginsenosides, the active components of ginseng, exhibit protective effects against inflammation, oxidative stress, and apoptosis, making them promise to treat various conditions

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Therefore, intrinsic cardiac load and capacity do not improve in patients with heart failure with reduced ejection fraction, and patients HFpEF benefit only from the treatment of abnormal metabolism and inflammation

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