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As tirzepatide is a relatively new medication whose side effect profile has yet to be fully characterized, clinicians should be aware of this rare yet potentially fatal complication. Although GLP-1 receptor agonists show impressive efficacy and favorable side effect profiles, it is necessary that we determine all risks and side effects, particularly rare ones, to minimize chances of poor outcomes, says the papers first author Eli J

doi: 10.2165/00003088-200342110-00002

Interaction of S100A8/S100A9-arachidonic acid complexes with the scavenger receptor CD36 may facilitate fatty acid uptake by endothelial cells

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Hyperactivation of PI3K/AKT signaling has been recognized as a major driver of COPD pathogenesis and airway inflammation, linking oxidative stress to structural damage of the airways and alveoli [37]