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Metformin: Immediate-Release (IR): Start with 500 mg twice daily or 850 mg once daily, gradually increase to 2,000 mg daily in divided doses

Adoption of the ADA/EASD guidelines in 10 Eastern and Southern European countries: physician survey and good clinical practice recommendations from an international expert panel

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Recent surveillance data suggests that the frequency of NAION reports is similar for semaglutide and tirzepatide, with preliminary incidence rates of approximately 8.9 per 100,000 person-years for semaglutide and 9.7 per 100,000 person-years for tirzepatide