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Diabetes Care 36, 19331940.CrossRefGoogle ScholarPubMed Scott, RA, Freitag, DF, Li, L, Chu, AY, Surendran, P, Young, R, Grarup, N, Stanckov, A, Chen, Y, Varga, TV and Yaghootkar, H (2016) A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

Seizures were not identified as a recognised adverse effect in the pivotal STEP (Semaglutide Treatment Effect in People with obesity) clinical trial programme, which enrolled over 4,500 participants and formed the basis for regulatory approval

[7] These remaining remnants of LDL can be sent back to the liver, where it can be stored for later use or broken down to harness its energy

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Administered as a once-weekly subcutaneous injection, it improves blood glucose control by stimulating insulin secretion, suppressing glucagon release, and slowing gastric emptying

Poor blood sugar control can lead to damage in the kidneys over time, a condition known as diabetic nephropathy