Clearance of senescent cells from injured muscle abrogates heterotopic ossification in mouse models of fibrodysplasia ossificans progressiva
Mechanistically, it influences gene networks involved in tissue remodeling and exerts protective antioxidant and anti-inflammatory actions, partly through TGF- signaling and regulation of metalloproteinases
Schrder M, Kaufman RJ (2005) The mammalian unfolded protein response
"Some people are deficient and feel a lot better when given a shot, but just to pep you up, there's no study that says it's helpful." B12 is created by bacteria, including those living in the digestive tract
It also stimulates synthesis of decorin, a small proteoglycan involved in collagen regulation and wound healing, while promoting the formation of new blood vessels and recruiting immune cells to the wound site
doi: 10.1097/00000441-200604000-00007