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GLP-1RAs and heart failure The prevalence of left ventricular ejection fraction (LVEF)-preserved heart failure continues to increase

GLP-1 receptor agonists in the treatment of type 2 diabetesState-of-the-art

Since GLP-1-induced insulin secretion requires glucose metabolism, we aimed to address the hypothesis that GLP-1 receptor (GLP-1R) signalling can modulate glucose uptake and utilization in -cells

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All these pathways eventually lead to an increase in the intracellular Ca 2+ concentration, thereby promoting the mitochondrial synthesis of ATP, and the release of insulin particles into the blood through exocytosis

The role of long chain fatty acids in regulating food intake and cholecystokinin release in humans