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It requires a medical evaluation, a BMI of 35 or higher or a BMI of 30-34 with a chronic health condition like heart disease or diabetes,[8] and a mental health screening (some require initial weight loss to prove commitment)

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Clinical trials are currently investigating whether restoring these cortical glutathione reserves can provide neuroprotection against oxidative stress

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doi:10.1210/endo.141.9.7680

Conclusion GLP-1RAs show significant promise as a potential disease-modifying therapy for neurodegenerative and inflammatory eye diseases, acting through both systemic metabolic improvements and direct ocular mechanisms, representing a paradigm shift beyond their metabolic indications