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In one study, 12-week treatment with insulin glargine vs liraglutide (mean dose = 1.3 mg/day) showed similar glycemic control and decrease of hepatic fat burden, although a reduction in BMI was only observed in the liraglutide-treated patients (68)

Collectively, these results show that IFN- increases surface HLA-I expression and peptide presentation

These findings prompted further investigation into the synthetic version of the peptide, now known as Epithalon, to better understand its mechanisms of action and potential applications in human health

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Clinical Management If glucocorticoid therapy cannot be paused, consider timing sermorelin injections at least 4 hours after the last glucocorticoid dose to take advantage of the circadian nadir of endogenous cortisol

doi: 10.1016/0020-7292(91)90645-l 39 LundmanBAsplundKNorbergA