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13), we could not record measurable currents from these receptors

However, we mitigated potential unmeasured confounding effects by employing proxy variables, (e.g., DCSI was used for diabetes severity and obesity surgery was used to identify morbidly obese patients)

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Peroxynitrite is highly toxic to neurons and causes hyper-excitability of the central nervous system, a process known as "kindling." This leads to autonomic nervous system dysfunction (dysautonomia), sensory overload, and severe cognitive deficits