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Stomach cramps may also occur on account of the ingredient vitamin C, which can be administered at a lower concentration if desired

& Seino, Y

By Bryan Briegel | 5 min

Skin reactions are often treated with topical corticosteroids for grade 3 toxicities or higher

Though the clinical significance has not been clearly established, notable changes (increases and decreases) from baseline in blood pressure and pulse rate were observed more commonly in pediatric patients treated with topiramate compared to those treated with placebo during migraine prophylaxis trials