Effects of exendin-4, a glucagon like peptide-1 receptor agonist, on neutrophil count and inflammatory cytokines in a rat model of endotoxemia
With the in-depth theory of the gutbrain GLP-1R axis, the breakthrough of new material technology and the rapid development of AI-assisted drug design, GLP-1R-related research has also ushered in new opportunities
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For those unfamiliar, GLP-1 receptor agonists are prescription medications that mimic the GLP-1 hormone that stimulates insulin release, suppresses appetite and slows digestion
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By binding to regional receptors in the gastrointestinal tract, GLP-1s alter gut motility in different areas of your intestines, affecting the physical contractions which push food (and waste) through your body