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We have determined that the brain angiotensin and HGF/c-Met systems interact in such a way that angiotensin IV (AngIV)-based analogs including Nle1-AngIV, Norleual-AngIV, Dihexa, and others influence HGF dimerization which is a prerequisite to binding at the Met receptor

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It therefore comes as no surprise that increasing the production of new neurons in the hippocampus enhances various cognitive functions, including learning and memory [62], object recognition [63], cognitive representations [64] and forgetting [65] (for review see ref