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Muscle preservation: AOD 9604 does not affect muscle

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia 16 (3): 399403

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Depression and fatigue Supports energy metabolism and neurotransmitter function

This inhibition preserves nicotinamide availability for the NAD+ salvage pathway, the primary route for NAD+ regeneration in mammalian cells

Safety: While both compounds show promise, AOD 9604 lacks extensive clinical trials, raising questions about its long-term safety compared to Semaglutide, which boasts a robust safety profile