Mechanisms of Action: Homing, Differentiation, and Paracrine Signaling Muse cells appear to work via a three-engine mechanism , grounded in modern regenerative biology: Targeted homing Damaged tissues release gradients of S1P (sphingosine-1-phosphate) and SDF-1 (stromal cell-derived factor 1, also known as CXCL12)
References Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM
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