tirzepatide for kidney disease (Zepbound) showed improved function in obese patients with both chronic kidney and #heartfailure with preserved ejection fraction, highlighting its potential to address this high-risk patient population. Read more: https Cardiorenal benefits of tirzepatide. By

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Wegovy is FDA approved for chronic weight management in adults with obesity and overweight with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol

The decision to use diabetes medications in any combination outside standard guidance would usually be made by a diabetes specialist, taking into account your specific clinical circumstances and with a clear rationale and review plan

Building on these data, here we assess whether the metabolic effects of such an incretin-conjugated PPAR agonist could further be enhanced by covalent tethering of Tesa to the peptide backbone of the DPP4-protected GLP-1RGIPR co-agonist MAR709 32 (Extended Data Fig

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