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PMID: 37820768 Mater Today Chematerials Today Chemistry 12 (2019) 78e84 J Med Chem Discovery of Novel P2Y14R Inhibitors for Ameliorating Liver Fibrosis by Suppressing Hepatic Stellate Cell Activation

Understanding this principle helps explain why jumping doses or rushing escalation consistently produces poor outcomes, even when the same final maintenance dose would be well tolerated with proper progression

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If you experience these, contact your physician immediately for dose adjustment