Gut barrier integrity tight junction organization and epithelial resilience*
Pregnancy depletes vitamin D stores, and most postpartum women are deficient
Control mice are often given a saline injection instead
The abundance of Faecalibacterium , a key genus responsible for SCFAs production, was significantly reduced, potentially leading to diminished butyrate synthesis and impaired gut homeostasis, while the abundance of proinflammatory bacteria Prevotella increased significantly (Li et al., 2024)
Li, G., Zhao, M., & Zhao, L
In particular, increased plasma insulin concentrations stimulate the gonadotropin releasing hormone (GnRH) pulsatility and potentiate the LH-dependent effect on the ovarian theca cells, leading to the enhanced synthesis of androgens and to the arrest of pre-antral follicle development [13]