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Notably, PI3K-Akt signaling plays an important role in glucose and lipid metabolism (Huang et al., 2018)

It remains an investigational compound moving through Eli Lillys Phase 3 TRIUMPH clinical program

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Functionalizing J211 with Lys(-(AEEA) 2 -E-stearate) (C 18 lipid dicarboxylate) at position 26 yielded mono-lipidated J229 (Fig

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