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DSIP is a naturally occurring nonapeptide studied in sleep and neuroregulatory research

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292 In addition, intermittent hypoxia induces the sympathetic nervous system to increase vascular resistance, down-regulates expression of the kallikrein-kallistatin vasodilator pathway, and activates the renal renin-angiotensin-aldosterone system to cause vasoconstriction

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Some of the storms extended 60 miles (100 km) below the cloud tops and others, including the Great Red Spot, extended over 200 miles (350 kilometers)