This paradoxical phenomenon is known as the "levee effect" (White,1958 Burby, 2006 Ding et al., 2023)
Structural and Molecular Biology 20, 929935
Nerve injuries: In sciatic nerve transection models, early axonal sprouting is detectable histologically within the first 714 days (Gjurasin et al., 2010)
& Deacon, C
Unlike apoptosis, paraptosis does not hinge on caspase activity but frequently hinges on the activation of mitogen-activated protein kinases (MAPKs), such as MAPK8/JNK, MAPK14/p38, and mitogen-activated protein kinase kinase 2 (MAP2K2/MEK2) [148]
Building on these tools, new dual agonist fluorescent probes such as daLUXendins enable the simultaneous investigation of GLP1R and GIPR (glucose-dependent insulinotropic polypeptide receptor), a critical advancement for studies on multi-agonist therapeutics in diabetes and obesity