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More studies reported that MTHFR C677T is associated with risk of depression, such as postmenopausal depression 70 and childhood trauma related major depression disorder (MDD) 71

This sequence is believed to play a role in rheumatic fever and glomerulonephritis

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Type-2 diabetic animal studies have revealed that butyrate has similar effects to metformin in reducing insulin resistance and other T2DM-associated conditions (60)

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