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Frick MA, Woodruff JL, Caudillo YM et al (2025) Orexin/Hypocretin modulates neuroinflammatory response to LPS in a sex and brain-region specific manner in young rats

It also boosts insulin production and lowers blood sugar directly

They are used as injections in addition to a diet and exercise program to control blood sugar in adults with type 2 diabetes

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doi: 3 10.1111/obr.12266

57 Similar recommendations have been made by Australian experts