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Extracellular superoxide dismutase deficiency and atherosclerosis in mice

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In this context, several microbiota-derived metabolites, including SCFAs, trimethylamine (TMA), bile acids, coprostanol, phenylacetylglutamine, and lipopolysaccharide (LPS), have gained attention due to their established involvement in cardiovascular diseases (21)

292 In RSV-infected airway epithelial cells, NOX-generated ROS trigger the activation of the transcription factors IRF and STAT, thereby inducing the expression of chemokines and cytokines involved in the immune/inflammatory responses of the lung