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While this review has focused on synthetic molecules with potential XO inhibitory activity, it is important to note the growing interest in natural products, including flavonoids, alkaloids, and terpenoids, which have demonstrated significant XO inhibition

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Instead of opting for high-dose, single-ingredient products, you can opt for combinations that support absorption, antioxidant balance, and skin health

doi: 10.3390/jcm11154611 7

Despite extensive research, technical development and clinical experimentation, no current surgery-based, material-based, cell-based or drug-based treatment can reliably restore the structure and function of hyaline cartilage