GLP-1 agonists such as Wegovy (semaglutide) and Zepbound (tirzepatide) have demonstrated up to 20% body weight reductions in pivotal trials an efficacy previously thought achievable only through bariatric surgery
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doi: 10.1007/s10545-006-0199-x, PMID: [DOI] [PubMed] [Google Scholar] 41.Salguero Olid A, Blanco Sanchez G, Alonso OA
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Wood LG, Gibson PG, Garg ML
But in the nference study, the risk was higher with tirzepatide regardless of how much weight patients lost or how much of the drug they received, which suggests that other explanations for hair loss may need to be considered, the researchers said