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461 During regeneration, TRIB1 downregulation permits NRF2 nuclear translocation, activating antioxidant response and fostering a conducive environment for hepatocyte proliferation

"Erythrocyte glutathione synthetase deficiency leads not only to glutathione but also to glutathione-S-transferase deficiency"

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In apoptosis, -sitosterol upregulates pro-apoptotic factors such as p53 and Bax, while downregulating anti-apoptotic proteins such as Bcl-2, leading to an increase in mitochondrial outer membrane permeability and the activation of key apoptotic enzyme cascades such as caspase-9 and 3, which induces programmed cell death (83)

doi: 10.1124/dmd.111.041673

Vitamin A and carotenoids as antioxidants in a physiological context