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The acyl-coenzyme A (CoA) synthetase long-chain family (ACSL) located on the mitochondrial outer membrane and endoplasmic reticulum (ER) can catalyze the transformation of fatty acids to acyl-CoAs (11)

Expression of key genes such as BDNF and Arc is governed by histone acetylation and DNA methylation, processes controlled by enzymes like histone acetyltransferases (HATs) and DNA methyltransferases (DNMTs) [215, 216]

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