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Hoffman et al, 2001)

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[DOI] [PubMed] [Google Scholar] 22.Levine J.S., Allen R.H., Alpers D.H., Seetharam B

Moreover, SLE patients with renal involvement exhibited significantly higher serum KYN levels and KYN/TRP ratios than those without renal damage, suggesting that activation of the kynurenine pathway may exacerbate glomerular mesangial cell injury via pro-oxidative mechanisms [51] (Fig