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Among these proteins, ATF4, ATF5, and ATF6 play distinct roles in modulating autophagy, particularly under nutrient deprivation, hypoxia, oxidative stress, and ER stress

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antioxidants Detoxification: Glutathione plays a key role in the detoxification of harmful substances, including drugs, pollutants, and carcinogens

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The mitochondrial dysfunction of TECs might be related to excessive formation of ROS and kidney damage in mouse models of IRI-AKI

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