Sales of GLP-1s have exploded in recent years
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Phase 2 data (Jastreboff et al., NEJM 2023) showed mean pulse rate increases of approximately 3 to 5 beats per minute at higher doses, consistent with known GLP-1 receptor agonist pharmacology
It does this by mimicking the effects of GLP-1, GIP and natural hormones that makes humans feel full from eating much smaller portions of food
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