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PGC-1 inhibition (PGC-1i) increased sensitivity to dual inhibition across subtypes, further supporting a central role of mitochondrial metabolism (Fig

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According to the National Academies of Sciences, Engineering, and Medicine (NAP), a safe highest level is called the tolerable upper intake level. Assessment of what amount is too much is based on animal and human studies, published evidence of adverse events, and professional agreement based on a committee of experts

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