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The STEP 8 trial showed semaglutide achieved 15.8% weight loss compared with 6.4% for liraglutide over 68 weeks

Regarding lipids metabolism, multiple studies have confirmed its close correlation with epilepsy: for example, sphingosine 1-phosphate can protect mitochondrial structure and function to alleviate neuronal hyperexcitability and damage in patients with DRE (143)

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[7] The active ingredient, semaglutide, works by mimicking the action of the naturally occurring hormone GLP-1, which is released by the intestine in response to food intake

Previous studies have proposed that phosphorylation of ERK1/2 promoted cell migration, proliferation, and metastasis in OSCC (Chang et al

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