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Visible body composition changes, including fat loss and lean muscle definition, become apparent between weeks 6 and 12

Clinical evidence consistently demonstrates that GLP-1RAs exert cardioprotective effects, including a significant reduction in the risk of MACE, alleviation of heart failure-related symptoms, and delay in the progression of atherosclerotic lesions

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5 Moreover, GLP-1 RAs have demonstrated cardioprotective properties that are independent of weight loss by reducing the content of systemic inflammation markers

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